Why Choose Us?

  • Team of eight doctors including haematologists and haemato-oncologists.
  • Completed over 1000+ bone marrow transplants.
  • 22-bedded transplant unit
  • One of the largest centres for multiple sclerosis, sickle cell and aplastic anaemia treatment
  • Global standard of infection control practises
  • One of the few centres performing matched unrelated donor transplant for thalassemia
  • Already treating patients from 18 different countries

 

Experts at the Department are experienced at treating different conditions including:

  • Anaemia
  • Sickle Cell Disease
  • Immune Deficiency Disorders
  • Thalassemia Major
  • Autoimmune Disease
  • Acute Myeloid Leukemia
  • Acute Lymphoblastic Leukemia
  • Multiple Myeloma
  • Clotting Disorders
  • Bleeding Disorders
  • Paediatric Solid Tumours (Ewings / Osteosarcomas / Neuroblastomas)

BONE MARROW TRANSPLANT

Bone marrow in our bones is responsible for formation of blood cells. In fact, all the blood cells are formed by a subset of bone marrow cells known as “hematopoietic stem cells” or simple “stem cells”. These blood cells have special characteristics i.e. they can renew themselves, and have the capability to develop into any type of blood cells. Nowadays, hematopoietic stem cells can also be obtained from peripheral blood after treatment with certain growth factors or from umbilical cord. Thus, “Hematopoietic stem cell transplantation” is now preferred to “Bone marrow transplantation”, wherein the stem cells from bone marrow that produce red blood cells, white blood cells, and platelets are injected into a recipient after a short course of chemotherapy called conditioning. Today, this is a viable option for several disorders and with a continued research, success has remarkably improved.

Different Types of BMT

An interesting observation here is that the type of bone marrow used for transplant is different from the different types of BMT. There are two types of BMT:

Allogenic BMT:

Donor and Recipient are two separate individuals and BMT is done using the stem cells of donor. It may be:

Matched Related, where donor is HLA matched relative usually a sibling.

Matched Unrelated, where donor is not a relative of patient and usually found from one of the various national or international registries.

Partially Matched Related, where donor is from a patient’s family but partially matched (haploidentocal).

Autologous BMT:

Donor and Recipient are same individuals. BMT is done using the patient’s own stem cells. The procedure involves giving high dose chemotherapy to patient in order to remove primary disease. Thereafter, an autologous transplant is conducted to rescue damaged bone marrow. This type of transplant has minimal complication and is preferred for diseases like multiple myeloma.

Who requires BMT?

There are certain conditions for which BMT is recommended.

Blood cancers

Multiple Myeloma

Hodgkin Lymphoma

Non-Hodgkin Lymphoma

Acute Lymphoblastic leukemia (ALL)

Acute Myeloid Leukemia (AML)

Chronic Myeloid Leukemia (CML)

Myelodysplastic syndrome

Non Cancerous Conditions:

Thalassemia, sickle cell anemia, transfusion dependent anemia

Aplastic anemia

Fanconianemia, pure red cell aplasia

Metabolic disorders

Immunodeficiency states

Are there any risks associated with BMT?

Yes, BMT is a complex procedure that carries significant risks of serious complications. Generally, the risks are reduced if:

you are young – studies have shown the younger you are, the more likely the treatment is to succeed

you receive stem cell donation from a sibling (brother or sister)

you have no serious health conditions (apart from the condition you're being treated for)

The major problem with stem cell transplants is the recipient's ability to withstand high doses of chemotherapy (and sometimes radiotherapy), which are often needed before the transplant.

Is BMT a surgery like kidney transplant?

No, Bone Marrow Transplant is a medical procedure. Mostly, stem cells are collected via peripheral vein and the whole procedure is like donating blood or platelet. In some patients Bone marrow harvest is done which involves general anaesthesia to the donor.

About Fortis Memorial Research Institute

Fortis Memorial Research Institute is a multi-super-speciality, quaternary care hospital with an enviable international faculty, reputed clinicians, including super-sub-specialists and speciality nurses, supported by cutting-edge technology.

A premium referral hospital, it endeavors to be the ‘Mecca of Healthcare’ for Asia Pacific and beyond. Set on a spacious 11-acre campus with 1000 beds, this ‘Next Generation Hospital’ is built on a foundation of ‘Trust’ and rests on four strong pillars: Talent, Technology, Service and Infrastructure.

Doctor's Profile

Dr. Rahul Bhargava

Director & HOD

Hematology, Hemato Oncology & BMT

Dr. Vikas Dua

Additional Director & HOD

Pediatric Hematology, Hemato Oncology & BMT

Dr. Meet Kumar

Consultant

Hematology, Hemato Oncology & BMT

Dr. Mansi Sachdev

Consultant

Pediatric Hematology, Hemato Oncology & BMT

Dr. Sachin Bansal

Associate Consultant

Hematology, Hemato Oncology & BMT

Dr. Minakshi Bansal Vohra

Attending Consultant

Pediatric Hematology, Hemato Oncology & BMT

Dr. Sohini Chakraborty

Attending Consultant

Pediatric Hematology, Hemato Oncology & BMT

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