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10 things you should know about hepatitis | Fortis Memorial Research Institute
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Gastroenterology and Hepatobiliary Sciences

10 things you should know about hepatitis

by Dr. Avnish Seth on Aug 01, 2018

According to Dr. Avnish Seth, Director, Gastroenterology at Fortis Memorial Research Institute- “For the World Hepatitis Day 2018, with the theme of “Eliminate Hepatitis” the WHO has already redefined their mission. However in India, there is no definite reporting for Hepatitis and we are far from eliminating this disease. Chronic Hepatitis is a silent killer and can go undetected for decades, causing severe damage to the liver. Hence, prevention and early detection is the key. The bad news is that among the types of Hepatitis viruses – A, B, C, D & E, vaccine is available for only Hepatitis A & B and many of us cannot recall whether we received vaccination or not.”

According to WHO- “Viral Hepatitis B and C are major health challenges, affecting 325 million people globally. They are root causes of liver cancer, leading to 1.34 million deaths every year. Hepatitis B and C are chronic infections that may not show symptoms for a long period, sometimes years or decades. At least 60% of liver cancer cases are due to late testing and treatment of Hepatitis B and C. Low coverage of testing and treatment is the most important gap to be addressed in order to achieve the global elimination goals by 2030.”

10 things you should know about hepatitis:

  • There are 5 types of Viral Hepatitis – A, B, C, D and E.
  • While Hepatitis A and E are transmitted by ingestion of contaminated food, Hepatitis B and C are transmitted by blood transfusion, unprotected sex and tattoos. Hepatitis D occurs only in patients with Hepatitis B.
  • By the age of 10 years, more than 95% children are already positive for Hepatitis A indicating poor sanitation and hygiene in the country. Hence, there is limited role for vaccination against Hepatitis A in adults.
  • Hepatitis E is the most common cause of Acute Viral Hepatitis in adults in India. Unhygienic street food is a major culprit.
  • Acute Hepatitis A and E are usually self-limiting and no specific anti-viral medication is required. The illness lasts for 2 to 3 weeks resulting in tremendous loss of man-hours. One in 1000 develop Acute Liver Failure and may succumb without liver transplant.
  • Hepatitis B and C tend to get chronic and may remain in the body life-long.
  • Following entry of virus into the body It may take 5 to 10 years for Hepatitis B and 20 to 30 years for Hepatitis C to produce liver disease.
  • All newborns have been receiving free vaccination against Hepatitis B for over 10 years. Adults need to take 3 doses of the vaccine at 0,1 and 6 months after making certain that they are not positive for HBsAg.
  • Booster dose for Hepatitis B is required only for high-risk individuals such as health care professionals if the antibody titre is less than 10 IU/L.
  • Effective anti-viral treatment is available for Chronic Hepatitis B and C. Treatment of Hepatitis C is for 12 to 24 weeks. For Hepatitis B, treatment is life-long.

The following chart will explain everything about hepatitis that you should know:


About Hepatitis Symptoms Vaccine
Hepatitis A is transmitted by consumption of contaminated food and water. The best way to eat safe and avoid street food. Come summer and rains, the fear of hepatitis A increases. Symptoms: loss of appetite, fever, high colored urine, jaundice, nausea and vomiting Vaccine: Available. Recommended for all children above 1 year and adults who are IgG-antiHAV negative. Two doses needed, at 0 and 6 months. No booster required.
Hepatitis B virus (HBV) is caused by entry of infected blood, body fluids or tattoos  Symptoms: Acute type - loss of appetite, fever, high colored urine, jaundice, nausea and vomiting
Chronic type- may have no symptoms for years, but may show up as cirrhosis later.
Vaccine: Available. Three injections are given (from newborn to adults) at 0, 1 and 6 months
Hepatitis C Virus (HCV) is caused by entry of infected blood, body fluids or tattoos  Symptoms: Acute type is very rare Chronic type- may have no symptoms for years, but may show up as cirrhosis later. Vaccine: None.
Hepatitis D Virus- infection occurs only in patients infected with Chronic HBV Symptoms: Same as Chronic Hepatitis B Vaccine: None. Prevention against HBV is the key
Hepatitis E Virus- is transmitted by consumption of contaminated food and water. Can be dangerous in pregnancy. Symptoms: Jaundice, appetite and weight loss, nausea, enlarged and tender liver.
Transmitted by oral route, i.e., going through contaminated food and water to end up in your food, including uncooked shellfish, much like HAV.
None

Dr. Avnish Seth

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